Alexandre Umpierrez Amaral Selected Research

3-hydroxypalmitic acid

1/2018

High vulnerability of the heart and liver to 3-hydroxypalmitic acid-induced disruption of mitochondrial functions in intact cell systems.

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Alexandre Umpierrez Amaral Research Topics

Disease

6	Mitochondrial Diseases (Mitochondrial Disease) 10/2021 - 08/2014
5	Glutaric Acidemia I 11/2019 - 09/2012
4	Brain Injuries (Brain Injury) 01/2022 - 11/2012
4	Neurologic Manifestations (Neurological Manifestations) 12/2020 - 02/2011
4	Propionic Acidemia 01/2020 - 07/2011
4	Ethylmalonic encephalopathy 01/2017 - 01/2012
3	Liver Diseases (Liver Disease) 10/2021 - 06/2015
3	VLCAD deficiency 02/2020 - 01/2018
3	Peroxisomal Disorders (Peroxisomal Disorder) 06/2013 - 03/2011
2	Brain Diseases (Brain Disorder) 12/2020 - 01/2020
2	Gliosis 10/2019 - 01/2018
2	Trifunctional Protein Deficiency With Myopathy And Neuropathy 01/2018 - 06/2015
2	2-Hydroxyglutaricaciduria 01/2018 - 06/2015
2	Short chain Acyl CoA dehydrogenase deficiency 08/2014 - 01/2012
1	Maple Syrup Urine Disease 01/2022
1	Inflammation (Inflammations) 12/2020
1	Alzheimer Disease (Alzheimer's Disease) 11/2020
1	Periodontal Diseases (Periodontal Disease) 10/2020
1	Muscular Diseases (Myopathy) 02/2020
1	Lactic Acidosis 01/2020
1	Cardiomyopathies (Cardiomyopathy) 01/2020
1	Demyelinating Diseases (Demyelinating Disease) 10/2019
1	Hypermethioninemia 07/2018
1	Mevalonate Kinase Deficiency 09/2017
1	Rhabdomyolysis 10/2016
1	Medium chain acyl CoA dehydrogenase deficiency 01/2016
1	Inborn Errors Metabolism (Inborn Errors of Metabolism) 11/2015
1	Metabolic Diseases (Metabolic Disease) 05/2015
1	Sulfite oxidase deficiency 12/2013
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 06/2013
1	Refsum Disease (Refsum's Disease) 06/2013
1	Atrophy 11/2012
1	Brain Edema (Cerebral Edema) 11/2012
1	Nonketotic Hyperglycinemia 08/2011
1	Methylmalonic acidemia 07/2011

Drug/Important Bio-Agent (IBA)

10	AcidsIBA 01/2022 - 09/2012
9	Glutaryl-CoA DehydrogenaseIBA 12/2020 - 09/2012
6	Fatty Acids (Saturated Fatty Acids)IBA 02/2020 - 06/2015
5	Biological ProductsIBA 10/2021 - 02/2011
5	Lysine (L-Lysine)FDA Link 11/2019 - 02/2011
3	Oxidoreductases (Dehydrogenase)IBA 01/2022 - 06/2015
3	Long-Chain Acyl-CoA Dehydrogenase (Long-Chain-Acyl-Coenzyme A Dehydrogenase)IBA 02/2020 - 01/2018
3	EnzymesIBA 11/2019 - 11/2012
3	Adenosine Triphosphatases (ATPase)IBA 07/2018 - 02/2011
3	ethylmalonic acid (ethylmalonate)IBA 05/2015 - 01/2012
2	S-Adenosylmethionine (Ademetionine)IBA 10/2021 - 07/2018
2	Amino Acids FDA Link 12/2020 - 02/2011
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 11/2015
2	Hydroxyl RadicalIBA 01/2018 - 06/2015
2	AntioxidantsIBA 01/2017 - 06/2015
2	Carnitine (L-Carnitine)FDA LinkGeneric 01/2016 - 06/2015
2	Acyl-CoA Dehydrogenase (Medium-Chain Acyl-Coenzyme A Dehydrogenase)IBA 01/2016 - 05/2015
2	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2015 - 03/2011
2	Succinic Acid (Succinate)IBA 08/2014 - 03/2012
1	Branched-Chain Amino AcidsIBA 01/2022
1	Keto AcidsIBA 01/2022
1	Leucine (L-Leucine)FDA Link 01/2022
1	Adenosine KinaseIBA 10/2021
1	Mitochondrial DNA (mtDNA)IBA 10/2021
1	AdenosylhomocysteinaseIBA 10/2021
1	Glycine N-Methyltransferase (Glycine Sarcosine N-Methyltransferase)IBA 10/2021
1	Carboxylic AcidsIBA 12/2020
1	LipopolysaccharidesIBA 12/2020
1	Amyloid (Amyloid Fibrils)IBA 11/2020
1	Scopolamine (Hyoscine)FDA Link 10/2020
1	CalciumIBA 01/2020
1	Propionyl-Coenzyme A Carboxylase (Propionyl CoA Carboxylase)IBA 01/2020
1	HydroxylysineIBA 11/2019
1	Tryptophan (L-Tryptophan)FDA Link 11/2019
1	maleic acid (maleate)IBA 08/2019
1	3-hydroxypalmitic acidIBA 01/2018
1	Adenosine Triphosphate (ATP)IBA 01/2018
1	3-Hydroxyacyl-CoA DehydrogenaseIBA 01/2018
1	Myristic Acid (Tetradecanoic Acid)IBA 01/2018
1	mevalonolactoneIBA 09/2017
1	Mevalonic Acid (Mevalonate)IBA 09/2017
1	Phosphotransferases (Kinase)IBA 09/2017
1	Hydrogen Sulfide (Sulfide, Hydrogen)IBA 01/2017
1	Sulfides (Thioethers)IBA 01/2017
1	Vitamin K 3 (Menadione)FDA Link 01/2017
1	Quinolinic AcidIBA 11/2016
1	Mitochondrial Trifunctional ProteinIBA 10/2016
1	2-methylcitric acidIBA 04/2016
1	Mitochondrial Permeability Transition PoreIBA 01/2016
1	Decanoic AcidsIBA 01/2016
1	Ketoglutaric Acids (Ketoglutaric Acid)IBA 06/2015
1	Riboflavin (Vitamin B2)FDA LinkGeneric 06/2015
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 09/2014
1	ThiosulfatesIBA 12/2013
1	SulfitesIBA 12/2013
1	Phytanic AcidIBA 06/2013
1	NAD (NADH)IBA 03/2012
1	malic acid (malate)IBA 03/2012
1	Glutamic Acid (Glutamate)FDA Link 03/2012
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 08/2011
1	Methylmalonic AcidIBA 07/2011
1	propionic acid (potassium propionate)IBA 07/2011
1	pristanic acidIBA 03/2011

Therapy/Procedure

1	Protein-Restricted Diet (Diet, Protein Restricted) 06/2015
1	Therapeutics 06/2015